Q10 Coenzyme

Q10 Coenzyme cover


The coenzyme Q10 has been the subject of frequent recent issues. As the body’s own substance, we partly absorb it with our food, but also form it in the body. The coenzyme takes many different functions in our organism was. In particular, it is involved in the provision of energy in the cells. Therefore, organs with a high energy requirement, such as our heart, lungs or liver, have high coenzyme concentrations. The coenzyme occurs in various forms in our body, which is why names such as ubiquinol and ubiquinone are also common. In recent years, the coenzyme has been known as an anti-aging agent, among other things. It can support our health in many ways. Heart health in particular is to be mentioned here. Last but not least, we feel a Q10 effect even in case of fatigue and exhaustion. In the case of dietary supplements containing the coenzyme, the bioavailability of the product is particularly important for a noticeable effect. Not all products are absorbed equally well by the body. Products with the coenzyme in liposomal form have a particularly high bioavailability.

What is Q10

1. What is Q10?

The coenzyme Q10 is a vitamin-like and fat-soluble body substance. It occurs in our organism as ubiquinol and ubiquinone. The substance is considered a vital substance as it has an important role in the energy formation of the body cells. In addition, it has antioxidant properties and affects the health of certain organs, especially the heart. The coenzyme is contained in various foods. As the body ages, the body’s formation of the substance decreases. In addition, in various life situations, such as under stress and in case of illness, the need may be increased.

It is disputed whether a deficiency of the coenzyme, apart from severe heart disease, can arise.

However, recent research suggests that the supply of the valuable coenzyme may not always be guaranteed in every situation and could be at risk, especially in old age.

Coenzymes and enzymes take on catalytic functions in the human body. This means that they make certain reactions possible through their presence. The cofactor is distributed throughout the organism, but especially in the organs with a high energy consumption as in the heart and muscles. Its name Ubi-Chinon (ubi- stands for everywhere) indicates its distribution throughout the body.

Q10 Coenzyme Guide nfi
How does Q10 work?

2. How does Q10 work?

As a vital substance, the coenzyme plays a key role in ensuring the energy supply in the body cells. Body cells have tiny power plants in their center. These are the mitochondria. In them arises the energy, which in the end makes up all the energy in the organism. The mitochondria are fed by a type of cell gasoline, the adenosine triphosphate. (ATP). ATP is formed in a specific process in which the smallest particles such as electrons and protons are active. For the activity of the smallest particles, the presence of sufficient coenzyme Q10 is absolutely necessary. If the cofactor is not present, the cell cannot form energy and dies at the end.

The Q10 effect on certain health disorders as well as degenerative processes such as aging has to do not only with the formation of energy in the cells. The coenzyme is also an antioxidant. Antioxidants make so-called free radicals harmless in our organism. Free radicals are aggressive oxygen molecules that strive for a connection with other molecules. They are biochemically very binding and therefore attack intact cells. This results in cell damage. Degenerative processes such as aging with wrinkle formation and other phenomena are associated with the activity of free radicals. One can imagine the activity of these aggressive particles in a similar way to the rusting of metal. Various vitamins, such as vitamins C and E as well as micronutrients such as selenium, have an antioxidant effect. This also applies to the coenzyme.

Summary: A potential Q10 effect is, for example,

  • the aging of the skin.
  • heart health.
  • the energy status of the entire organism.
  • the stability of the psyche.
  • blood pressure (influence on high blood pressure).
  • glucose metabolism (influence on diabetes mellitus).
  • Side effects of medications.
  • cell health in general (possible protection against malignant cell changes).


With the potential effect of the coenzyme, it should not be forgotten that the production of energy in the cells is not possible without this cofactor. Its importance is often underestimated. Our body cannot do without thissubstance. As its production decreases with age, supplemental supplements with the substance can become useful. This can also counteract a creeping loss of energy that characterizes the increasing age of many people.

Mitochondrial medicine is increasingly coming into focus. According to many experts in micronutrients (orthomolecular physicians) it has long been proven that typical age problems, fatigue and fatigue as well as many other diseases are due to a disturbed function of the cell power plants. [1] The need and supply of the coenzyme play a key role. Most people therefore benefit from high-quality dietary supplements as capsules or in the form of liposomal products. They have very good experiences when they absorb the coenzyme high-dose at 100 mg daily. This intake is in addition to a diet that is as rich as possible in the coenzyme. However, since the cofactor is sensitive to heat, it is difficult to estimate how much ubiquinol we feed daily with our food.

Best Q10

3. Which Q10 is the best?

High-quality products with the coenzyme have certain properties, so that the organism can benefit from an additional absorption of this cofactor via a dietary supplement. They help with a potential deficiency in which Q10 is used in high doses. They make the valuable cofactor particularly usable for the human body (high bioavailability) via forms of application such as liposomal form. For products with Q10 capsules, Q10 Forte from Yoyosan is an optimal dietary supplement. Users benefit from these benefits:

  • Q10 100mg in one capsule for use only once daily
  • valuable complementary extracts to increase the absorption of the coenzyme into the human body
  • Product comes from without additives
  • vegan dietary supplement
  • Manufacture according to the high requirements of GMP production
  • Purity of 99%


If you prefer a product in liquid form, you can also choose yoyosan liposomal Q10 as an alternative. In this type of product, the active ingredient is introduced into small beads (liposomals). These beads ensure an intensively increased absorption of the active ingredients into the body, because they are optimally protected from external influences during passage through the stomach and parts of the intestine. With this dosage form, bioavailability can be increased to 98%. This is why this Yoyosan product is high-dosed with 50 mg Q10. The liquid dosage form is also particularly easy to absorb. Yoyosan products are optimally formulated dietary supplement center with Q10 ubiquinol. Buying Q10 is a matter of trust.

Especially in products with Q10 ubiquinol, it plays a big role how much of the substance reaches the cells in the end. It should not be forgotten that the coenzyme must arrive directly in the cell itself in order to perform its most important function in the formation of energy by the mitochondria via the ATP metabolism. Products of low quality and low bioavailability have little benefit to users.

Only if it is ensured that the active ingredient from Q10 capsules can reach the cell interior, products can act with the coenzyme. In many cases, people also need Q10 high doses. Those who suffer from cardiovascular diseases, for example, could benefit from an additional 100 mg per day. Such a high dosage can also only be achieved with products that are very pure and send the active ingredient into the cell interior via a high bioavailability. It is therefore not worth buying inferior products with the cofactor.

Helps Q10

4. What complaints does Q10 help against?

Scientists and experts in the coenzyme assume that the substance reaches its highest level of the human body around the age of 20. The older we get, the more the production of the body’s own substance decreases. Our organism forms mainly in the heart, in the liver as well as in the kidneys reserves of the cofactor, whereby about 1-1.5 g are stored. Every day we only take 5-10 mg of the coenzyme with food. It is mainly found in oily fish, such as in sardines or mackerel, in meat (especially in the liver), in nuts, various seeds, vegetable oils and some vegetables such as broccoli. However, the coenzyme does not remain stable during cooking.

An increasing number of nutrition experts from physicians consider the intake of 60-100 mg Q10 ubiquinol to be appropriate, especially in advanced age. These requirements are often not achieved with the diet. In addition, certain diseases of the heart, such as myopathy, may experience a proven Q10 deficiency. In addition, some medicines, such as statins, increase the need for the coenzyme. [2] In the cardiovascular sector, many users experience a favorable Q10 effect for discomfort, loss of performance and for the prevention of signs of aging.

4.1 in the case of diseases of the heart

The heart is an organ that requires a lot of energy. In the case of heart disease, this need for more energy may be increased. This also increases the demand for Q10 ubiquinol. More common is even a Q10 deficiency trigger for heart problems.

Therefore, for heart disease, it is recommended to take Q10 high-dose as Q10 100mg capsules once daily.

With a dosage of up to 50 mg daily, heart health should be protected as a preventive measure. Overall, the adequate supply of the coenzyme can ensure that older people in particular fill up more vitally and energetically in terms of their own performance as well as the performance of the heart.

4.2 in case of high blood pressure

High blood pressure often leads to subsequent diseases, especially of the heart. In addition, high blood pressure costs the body a lot of energy overall. Most blood pressure medications also have a negative effect on the production of the coenzyme. This creates a Q10 deficiency. Higher demand and lower production are a dangerous combination. Therefore, high blood pressure patients could particularly benefit from the additional intake of capsules in high dosage. [3] Similar to heart disease, Q10 is highly dosed in capsules with Q10 100mg. The coenzyme helps high blood pressure patients to remain vital and energetic. The increased energy demand is intercepted and the load on the cardiovascular system is reduced.

4.3 in diabetes (diabetes mellitus)

Also, those who have diabetes can benefit from Q10 capsules. In diabetics, energy production in cells is often reduced by a reduced production of ATP. Diabetics have an increased energy requirement. In addition, the reduced production of ATP reduces the production of insulin in the cells of the pancreas. The coenzyme is therefore an important helper to keep the remaining in-house production of insulin stable and to prevent consequential damage of diabetes as far as possible. [4] In addition, the cofactor in diabetics convinces with its antioxidant power. Diabetes leads to an increased release of free radicals in the organism. This has something to do with the changed metabolic functions in diabetes. Diabetics should therefore also take 100 mg of the coenzyme daily with a high-quality dietary supplement such as Yoyosan.

4.4 When taking certain medications

Various medicines, such as lower blood pressure and statins, hinder the production of the cofactor. Especially people who suffer from high blood pressure or a disturbed cholesterol metabolism are particularly dependent on a supply with the coenzyme. Here they may be threatened with cardiac arrhythmias, a further increase in blood pressure or a weakness of the heart muscle. Those who need to take appropriate medicines could have additional health benefits of 100 mg of Q10 ubiquinol daily. This can prevent a potential Q10 deficiency.

4.5 in case of stress-related fatigue and exhaustion

Some life situations demand a lot of energy from the human organism. Since energy is provided in the body cells via the ATP metabolism, an increased need for energy always has something to do with the coenzyme. If this is not present to an increased extent, the cells cannot produce more energy.

When we are sick or under stress, our body needs more and more energy. Here, too, an additional intake of Q10 capsules is to be considered. They can help us to feel more vital and alive. In some cases, a dosage of 30-50 mg daily will suffice. If additional strains such as high blood pressure and the like are added, a dose of Q10 100mg daily may be additionally recommended.

4.6 on preventing and combating premature ageing

Many people today want to feel young for as long as possible and also postpone externally typical signs of aging such as excessive wrinkle binding for as long as possible. In doing so, they can benefit from the antioxidant potential of the cofactor. As a dietary supplement, Q10 capsules can help us to be vital and energetic even in advanced age. [5]

Our skin also benefits from the additional intake of the cofactor. Since the in-house production of the important substance decreases in old age, we not only replenish our stores with the additional intake, but also encounter a possible lack of this important substance. Hardly anyone can get past other illnesses in old age and often not a daily intake of certain medicines. In many cases, it may be recommended to absorb the coenzyme high-dose with 100 mg daily. In middle age, a dose of 30-50 mg per day may be sufficient.

4.7 for depression and lack of energy

Depression and depressive moods are often associated with a glaring lack of energy. Specialist physicians are also increasingly finding that imbalances in the psychic area often have something to do with the energy supply of the cells themselves. The term mitochondrial exhaustion is not yet familiar to many people. [6]

More and more doctors and scientists, however, see the cause of many degenerative diseases, as well as mental disorders such as depression, as the fact that the cell power plants can no longer produce sufficient energy.

This may also be associated with a deficiency of the coenzyme. Since all mental illnesses require an additional need for energy, an additional intake of ubiquinol may benefit. Again, a dosage of 100mg daily may be additionally appropriate.

4.8 on cell protection and the interception of side effects of cancer

The coenzyme contributes to cell protection due to its antioxidant properties. [7] If malignant cell changes are already present and are treated, for example, with chemotherapy or radiation, our organism is almost flooded by free radicals. All these cancer treatments therefore have intensive side effects and consequences. As a dietary supplement in high doses of at least 100 mg daily, Q10 capsules can help to alleviate and prevent possible cell damage to healthy cells. The attending physician should also be consulted.

Dosage and intake Q10

5. How to take Q10 or how to dose it?

The coenzyme is optimally absorbed by the body when consumed with a meal. Most people, especially in advanced age, benefit from Q10 100mg daily as a dietary supplement. In younger years without pressures in the cardiovascular area, it is generally considered that 10-50 mg daily is sufficient, because the body itself produces even more of the cofactor. Under medical supervision, coenzyme Q10 is supplemented in high doses of 200 mg. At a dosage of more than Q10 100mg per day, some people respond with gastrointestinal disorders and other side effects. In addition, an interaction with blood clotting inhibitors is possible. Those who take them should consult with their doctor before supplementing high-dose ubiquinol/ubiquinone.

Conclusion Q10

6. Conclusion: Why is Q10 so healthy?

Since already at a age of more than 20 years the in-house production of ubiquinol decreases in the human organism, a later Q10 deficiency is not excluded. This is not only true for old age. Various widespread diseases such as heart disease, high blood pressure or diabetes also quickly increase the need for energy and thus the coenzyme. A preventive Q10 effect can also be important at an early stage. It is also interesting that Q10 ubiquinol is a powerful antioxidant. According to current experts, many degenerative diseases, especially in old age, are due to the activity of aggressive oxygen molecules.

There are major differences in quality in the food supplements with the valuable coenzyme. These can be seen, among other things, in the bioavailability and thus the usability of the additionally supplied cofactor in the human organism. It is worth buying high quality Q10. In quality products, Q10 is high-dose and therefore usually only needs to be taken once a day. Only the highest quality products, with their convincing degree of purity, achieve the possibility of a possible Q10 deficiency being reduced or avoided in the first place. These products could also prove to be partners in the fight against premature ageing. Buying and absorbing high-quality Q10 can therefore also be a bit of an increased quality of life.

List of sources:

  1. https://www.ncbi.nlm.nih.gov/pubmed/32219756
  2. https://www.ncbi.nlm.nih.gov/pubmed/32182869
  3. https://www.ncbi.nlm.nih.gov/pubmed/32188111
  4. https://www.ncbi.nlm.nih.gov/pubmed/32179207
  5. https://www.ncbi.nlm.nih.gov/pubmed/32171384
  6. https://www.ncbi.nlm.nih.gov/pubmed/32124160
  7. https://www.ncbi.nlm.nih.gov/pubmed/32115970
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Autor: Giacomo Hermosa

Giacomo Hermosa ist 37 Jahre alt, Vater von zwei Kindern und verheiratet. Vor elf Jahren hat er die Magister der Biologie und Anglistik erfolgreich absolviert. Hier hat er sich interdisziplinär mit den Themen Bioverfügbarkeit und Medizinalhanf beschäftigt. In seiner Freizeit schreibt er v.a. in den Bereichen Fitness, Ernährung und – familiär bedingt – über einige besondere Autoimmunerkrankungen. Seine Veröffentlichungen findet man u.a. auf seiner Website und bei der taz.